Chinatown in Washington, D.C. is a small, historic neighborhood east of downtown, restaurants and small businesses along H and I Streets between 5th and 8th Streets, Northwest. It is known for its annual Chinese New Year festival and parade and the Friendship Arch, a Chinese gate built over H Street at 7th Street. Other prominent landmarks include the Verizon Center, a sports and entertainment arena, and the Old Patent Office Building, which houses two of the Smithsonian Museums. The neighborhood is served by the Gallery Place-Chinatown station of the Washington Metro.

In 2006, Chinatown went under a $200 million renovation, transforming the area into a bustling scene for nightlife, shopping and entertainment, with high-end restaurants, a deluxe movie theater and a number of new stores. Gentrification has produced a strange phenomenon in DC's Chinatown. The new businesses are national chain restaurants and stores, so that Starbucks, Hooters, CVS and Legal Sea Foods, among others, hang their names in Chinese outside their stores, which are either generic names of the store, or literal translations.

Chinatown's most prominent businesses are the approximately 20 Chinese and Asian restaurants, almost all of which are owned by Asian American families. Among the most famous are Szechuan Gallery, Burma, Eat First, Full Kee, and Tony Cheng's. One of the restaurants, Wok & Roll, occupies what was once Mary Surratt's boarding house — the meeting place for John Wilkes Booth and his conspirators in Abraham Lincoln's assassination. Another is located in a house once owned by the On Leong Chinese Merchants Association, which was among the first Chinese organizations to move into the neighborhood; today the structure is on the National Register of Historic Places.

The neighborhood is also home to a Chinese video store, a handful of general stores, and numerous Chinese-American cultural and religious charities. Recently, Chinatown has also become an independent transportation hub. Several independent, immigrant-owned Chinatown bus lines run from DC to the Chinatowns in Philadelphia, New York, and even Boston. They include MVP Bus and New Century Travel. Prices are generally set at just under Greyhound Bus fares.